The animated series "Fantastic Four: World's Greatest Heroes" does not feature any identifiable LGBTQ+ characters or themes. The narrative focuses on the superhero team's adventures without exploring queer identities or relationships, resulting in no direct portrayal to evaluate.

The animated series "Fantastic Four: World's Greatest Heroes" does not include any identifiable transsexual characters or themes. The show focuses on the traditional superhero adventures of the Fantastic Four, without engaging with transsexual identities or related storylines.

The show features Sue Storm (Invisible Woman) as a primary female character who participates in combat. However, her victories against male opponents are consistently achieved through the use of her superpowers (invisibility and force fields) to restrain or incapacitate, rather than through direct physical combat skills like martial arts or hand-to-hand fighting.

The animated series "Fantastic Four: World's Greatest Heroes" maintains the established genders for all its main and recurring characters, consistent with their comic book origins. No characters canonically established as one gender are portrayed as a different gender in this adaptation.

The animated series 'Fantastic Four: World's Greatest Heroes' portrays the core Fantastic Four characters (Reed Richards, Sue Storm, Johnny Storm, Ben Grimm) consistent with their established racial depictions in the Marvel Comics source material. No instances of a character's race being changed from their canonical portrayal were identified.