Grantchester features a central gay character, Leonard Finch, whose storyline sensitively explores the profound challenges of being a gay man in 1950s Britain. The series depicts his struggles with societal prejudice and legal persecution, framing these as external injustices. Despite the hardships, the narrative maintains an empathetic stance, portraying Leonard with dignity and complexity, ultimately affirming the worth of LGBTQ+ lives.

The series portrays family life within the traditional norms of 1950s England, depicting heterosexual marriage as the societal ideal and traditional gender roles as prevalent. While characters navigate personal struggles and challenges within these structures, the narrative generally frames established family values and community ties positively.

The series centers on an Anglican vicar, exploring themes of faith, morality, and redemption within a Christian framework. While individual characters face struggles and moral failings, the overall narrative portrays the church and its core tenets with respect and nuance, often aligning with Christian virtues.