L.A. Law offered a groundbreaking and largely positive portrayal of LGBTQ+ characters and themes for its time. It featured openly bisexual characters with dignity and explored various LGBTQ+ legal issues, consistently challenging prejudice and advocating for empathy and understanding.

L.A. Law featured a groundbreaking 1987 episode centered on Alex DePalma, a transsexual woman. The narrative respectfully portrays her legal battle for dignity after gender confirmation surgery, highlighting external societal prejudice and legal complexities. While depicting challenges, the show's overall stance is empathetic, affirming her identity and agency.

The show frequently explored Christian characters grappling with their faith and values in complex legal and ethical situations, often portraying their beliefs as a source of moral guidance or personal strength. While individual hypocrisy or institutional flaws might be depicted, the narrative generally treated the faith itself and sincere adherents with respect and nuance.

Jewish characters and their cultural or religious identity were consistently portrayed with respect and depth. The show often highlighted aspects of Jewish community, tradition, and ethical considerations, integrating these elements into character development and legal cases without resorting to negative stereotypes.