The Late Show with Stephen Colbert consistently offers an affirming portrayal of LGBTQ+ characters and themes. It provides a respectful platform for diverse LGBTQ+ guests and uses its commentary and comedy to support LGBTQ+ rights and critique discrimination, resulting in a net positive impact.

The Late Show with Stephen Colbert has consistently engaged with transsexual themes and characters through news commentary, interviews, and comedic segments. Its net impact is positive, as it generally critiques anti-trans prejudice, advocates for trans rights, and provides respectful platforms for transgender voices, framing obstacles as external societal issues.

When depicted, Buddhism is generally presented with respect, exploring its philosophical tenets or cultural practices in an appreciative and informative manner.

The show, through Stephen Colbert's personal reflections and respectful engagement, often portrays Christianity (especially Catholicism) with nuance, depth, and dignity, even when satirizing specific political or cultural manifestations.

When depicted, Hinduism is typically portrayed with respect, acknowledging its rich traditions, philosophical depth, or cultural contributions.

The show actively works to counter negative stereotypes and promote understanding of Islam, often through respectful dialogue, challenging prejudice, and showcasing diverse Muslim voices.

The show consistently treats Judaism with respect, often highlighting its cultural richness, celebrating shared values, and addressing issues affecting the Jewish community with empathy.

If depicted, Sikhism is generally presented respectfully, highlighting its principles, community, or cultural aspects.