The film features Little Horse, a 'he-she' (winkte) in Cheyenne culture, depicted with dignity and full acceptance by their tribe. The narrative portrays this third gender role as natural and respected, contrasting with Western norms. The overall impact is positive, affirming the worth of diverse identities through a culturally sensitive lens.

The film "Little Big Man" features Little Horse, a "he-she" (winkte) in the Cheyenne tribe, a respected third gender role. The character is portrayed with dignity and is fully accepted by their community, including marrying Jack Crabb's adopted sister. The narrative respectfully depicts this identity as a natural part of Cheyenne culture, offering a positive and affirming portrayal.

The film uses satire to depict Christian missionaries as hypocritical and lustful, and implicitly critiques the role of Christian-influenced ideology in justifying the violence and oppression of Native Americans. The narrative frames these portrayals as deeply flawed and problematic.