Based on the provided information, there is insufficient data to evaluate the portrayal of LGBTQ+ characters or themes in 'The Rational Life, 2021'. No specific details regarding their presence or depiction were available to determine a net impact.

There is currently not enough information available to assess the film's portrayal of transsexual characters or themes. The provided details do not indicate the presence of such elements, making a holistic evaluation impossible.

The movie does not contain any action or adventure elements.

There is no information provided to suggest that "The Rational Life" is an adaptation of a prior work or based on historical figures with established character genders. Without source material or prior canon, it's impossible to determine if any character's gender has been swapped.

There is no information indicating that "The Rational Life" is an adaptation of source material with established character races, nor does it feature historical figures. The cast is consistent with the production's likely origin, providing no basis to identify a race swap.