The series "Tom Clancy's Jack Ryan" does not feature any identifiable LGBTQ+ characters or themes across its seasons. The narrative primarily focuses on geopolitical espionage and action, with no discernible representation or exploration of queer identities or experiences.

Tom Clancy's Jack Ryan does not feature any identifiable transsexual characters or themes. The show's narrative is centered on espionage, counter-terrorism, and international political intrigue, with no elements related to transgender identity or experiences.

The series features several female characters in significant roles, including intelligence operatives and political figures. While some are involved in tense situations or tactical operations, none are depicted winning close-quarters physical combat against one or more male opponents. Their action sequences primarily involve strategic planning, intelligence gathering, or the use of firearms.

The series adapts characters from Tom Clancy's novels, such as Jack Ryan, Cathy Mueller, and James Greer. All major characters retain their established genders from the source material. No instances of a character canonically established as one gender being portrayed as another were identified.