Creature from the Black Lagoon, a 1954 monster film, does not include any discernible LGBTQ+ characters or themes. The story centers on a scientific expedition and its encounter with a prehistoric creature, with all human relationships depicted as heterosexual.

Creature from the Black Lagoon does not feature any identifiable transsexual characters or themes. The narrative is solely focused on a monster-thriller premise, thus the film has no impact, positive or negative, on the portrayal of transsexual identity.

The film features Kay Lawrence as the primary female character. She is frequently imperiled by the Gill-man, a male creature, but does not engage in or win any direct physical combat against him or any other male opponents. Her role is primarily that of a victim or observer.

This film is the original appearance of its characters. There is no prior source material or previous installment from which character genders could have been established and subsequently swapped.

This film is the original appearance of its characters. There is no prior source material or previous installments establishing the race of any character before this film's creation. Therefore, no character's race was changed from an established baseline.