The film "Empire of the Wolves" does not feature any identifiable LGBTQ+ characters or themes. The narrative focuses on a police investigation and a woman's amnesia, with all depicted relationships and character identities being heterosexual. Therefore, there is no LGBTQ+ portrayal to evaluate.

The film 'Empire of the Wolves' does not feature any discernible transsexual characters or themes within its plot or character arcs. Therefore, an evaluation of its portrayal is not applicable.

The film features Anna Heymes, who is frequently in peril and struggles against male antagonists. However, her survival and resolution of conflicts do not involve her physically defeating one or more male opponents in close-quarters combat through skill or strength. No female characters are depicted winning direct physical fights against male opponents.

The film "Empire of the Wolves" is an adaptation of Jean-Christophe Grangé's novel. The main characters, including Paul Nerteaux, Anna Heymes, and Jean-Louis Schiffer, maintain their established genders from the source material in the film adaptation.

The film "Empire of the Wolves" is an adaptation of a French novel. There is no evidence that any character, canonically established as one race in the source material, was portrayed by an actor of a different race in the film.