Ghostbusters: Frozen Empire does not explicitly portray transsexual characters or themes. While it features queer-coded subtext, particularly in the relationship between Phoebe and Melody, this is not directly identified as transsexual representation within the film. Therefore, there is no identifiable transsexual depiction.

Female characters like Phoebe and Callie Spengler participate in combat against supernatural entities using specialized Ghostbusters technology. However, the film does not depict any female character engaging in or winning close-quarters physical combat against one or more human male opponents.

The provided information indicates no direct evidence of gender-swapped roles or characters in Ghostbusters: Frozen Empire. The film continues with established characters, including new female protagonists introduced in the previous installment, without altering the canonical gender of any legacy or pre-existing characters.

The provided information indicates no explicit race swaps or notable shifts in racial portrayal for established characters in Ghostbusters: Frozen Empire. The inclusion of diverse actors in new, original roles does not meet the definition of a race swap.