Hotel for Dogs is a family-oriented comedy centered on children and animals. The film does not feature any identifiable LGBTQ+ characters, themes, or storylines, resulting in no depiction to evaluate.

The film "Hotel for Dogs" does not feature any identifiable transsexual characters or themes within its narrative. The story focuses on two orphaned siblings who create a shelter for stray dogs, with no elements related to transgender identity present.

The movie does not contain any action or adventure elements.

The film "Hotel for Dogs" (2009) is an adaptation of the 1971 novel. All major characters from the source material, such as Andi, Bruce, and their guardians, retain their original established genders in the movie adaptation. No instances of a character canonically established as one gender being portrayed as another were found.

The film "Hotel for Dogs" is an adaptation of a novel where character races were not explicitly defined or widely established. The casting choices for the film do not contradict any prior canonical or widely understood racial depictions, thus no race swaps occurred.