Inside Out 2 does not feature explicit LGBTQ+ representation or themes. The narrative centers on a young girl's universal emotional development, without exploring specific LGBTQ+ identities or experiences. Consequently, the film's portrayal of LGBTQ+ elements is not applicable.

Inside Out 2 does not explicitly portray transsexual characters or themes. While some viewers interpreted Riley's close friendship with Val as potentially queer-coded, the film ultimately presents their relationship as platonic. This reflects a cautious approach to queer representation, resulting in an absence of direct or meaningful depiction of trans identities rather than an affirming or problematic portrayal.

Inside Out 2 centers on Riley's emotional journey through adolescence, featuring her and her emotional personifications. The film emphasizes emotional strength and resilience rather than physical action or combat. There are no scenes depicting female characters engaging in or winning close-quarters physical fights against male opponents.

Inside Out 2 is a sequel where established characters retain their original genders. New emotions introduced are original to this film, not gender-swapped versions of prior characters. The film does not feature any instances of characters changing gender from previous canonical portrayals.

The film introduces new characters, such as Riley's friends Bree and Grace, who are depicted as African and Asian descent. However, these are new, original characters, and no previously established characters from the first film have had their race changed. Therefore, it does not meet the definition of a race swap.