Interstate 60 does not feature any identifiable LGBTQ+ characters or themes. The narrative focuses on a heterosexual protagonist's surreal journey of self-discovery, encountering various eccentric individuals and towns. The film's plot and character arcs do not address sexual orientation or gender identity in any capacity.

The film does not feature any identifiable transgender characters or explore themes related to transsexual identity. While a character attempts to legally change their gender, this is presented as a comedic plot device to exploit a contractual loophole, rather than a genuine portrayal or exploration of transgender experience.

The film does not feature any scenes where a female character engages in direct physical combat against one or more male opponents. The narrative focuses on a surreal road trip with philosophical encounters rather than physical confrontations.

Interstate 60 is an original story with characters created specifically for the film. There are no pre-existing canonical or historical figures whose gender could have been altered for this adaptation.

The film Interstate 60 is an original story with characters created specifically for this production. There are no pre-existing source materials, historical figures, or prior adaptations from which character races could have been established and subsequently altered.

Not depicted in the film.