John Wick: Chapter 2 does not feature any explicit LGBTQ+ characters or storylines. The film's plot is entirely centered on its action-thriller premise, resulting in no portrayal of LGBTQ+ themes, either positive, negative, or neutral.

John Wick: Chapter 2 does not feature any identifiable transsexual characters or themes. The narrative focuses exclusively on the criminal underworld and its rules, with no elements pertaining to transgender identity.

The film features Ares, a female character who engages in close-quarters combat with John Wick. While skilled, she is ultimately defeated by him in both their physical confrontations. No other female characters are depicted achieving victories over male opponents in direct physical combat.

John Wick: Chapter 2 is a direct sequel to the original film, continuing the established narrative and characters. All returning characters maintain their previously established genders, and new characters introduced in this installment do not have prior canonical gender baselines to swap from.

John Wick: Chapter 2 is a direct sequel where all returning characters are portrayed by the same actors, maintaining their established race from the previous installment. New characters introduced in this film do not qualify as race swaps under the given definition.