Due to the absence of specific information regarding LGBTQ+ characters or themes in 'Mondocane, 2021', a comprehensive assessment of its portrayal cannot be made. There is insufficient data to determine if such elements are present or how they are depicted within the narrative.

There is insufficient information available to assess the film's portrayal of transsexual characters or themes. Without plot details or character descriptions, it is not possible to determine if such elements are present or to evaluate their net impact as positive, negative, or neutral.

Based on available plot summaries and character descriptions, the film primarily focuses on male characters and their involvement in gang violence. While female characters are present, there is no information indicating any scenes where a female character defeats one or more male opponents in direct physical combat.

Mondocane is an original 2021 film and not an adaptation of pre-existing source material, nor does it feature historical figures. All characters are new to this production, meaning there are no established characters whose gender could have been swapped.

Mondocane (2021) is an original film, not an adaptation of existing source material or a biopic. Its characters were created for this specific production, meaning there is no prior established canon or historical record against which to assess a race swap.