The film 'Night at the Museum: Secret of the Tomb' does not feature any identifiable LGBTQ+ characters or themes. The narrative and character arcs are entirely devoid of any elements related to queer identity, resulting in no portrayal to evaluate.

Night at the Museum: Secret of the Tomb is a family-friendly adventure comedy. The film does not include any transsexual characters or explore related themes, resulting in no specific portrayal to evaluate.

The film features several female characters, including Sacagawea and museum guards Meredith and Tilly. However, none of these characters engage in or are depicted as victorious in close-quarters physical combat against male opponents. Their roles do not involve direct physical confrontation.

The film features historical figures and original characters from the franchise. All historical figures are portrayed with their documented gender, and all original characters maintain their established gender from previous installments. No character's gender was changed from their canonical or historical representation.

All returning characters maintain their established races from previous installments. New characters introduced in this film do not have a prior canonical or historical race that is altered, thus no race swaps occur.