Who Framed Roger Rabbit does not contain any explicit or implicit LGBTQ+ characters or themes. The narrative centers on a heterosexual detective and animated characters, with no elements that could be interpreted as LGBTQ+ representation, resulting in an N/A rating.

The film "Who Framed Roger Rabbit" does not feature any identifiable transsexual characters or themes. Its narrative focuses on a human detective and cartoon characters in 1940s Hollywood, without engaging with transgender identity in any capacity.

The film does not depict any female characters engaging in or winning direct physical combat against one or more male opponents. Female characters are present but do not participate in such action sequences.

The film adapts characters from the novel "Who Censored Roger Rabbit?" All major characters, such as Eddie Valiant, Roger Rabbit, and Jessica Rabbit, maintain their established genders from the source material. No character originally depicted as one gender is portrayed as another.

The film features human and animated 'toon' characters. All human characters are portrayed by actors matching their established or implied race from the source material. The 'toon' characters are not subject to the definition of human race swap.