Ben 10: Omniverse primarily focuses on apolitical themes of individual heroism, responsibility, and the universal struggle between good and evil. While promoting tolerance and understanding of diverse species, these themes are balanced by an emphasis on individual action and the responsible use of power, resulting in a neutral political stance.

The animated series features a visually diverse cast primarily through its wide array of alien characters, without explicitly altering established human roles for diversity. Its narrative maintains a neutral to positive portrayal of traditional identities, focusing on action and adventure rather than explicit critiques or central DEI themes.