Blue Eye Samurai does not feature transsexual characters or themes. The protagonist's cross-dressing is a survival mechanism in a patriarchal society, not an expression of gender identity. The series focuses on the struggles of women and mixed-race individuals, without engaging with trans experiences or representation.

The provided information describes Mizu as a skilled character who might engage in solo combat. However, it does not detail specific scenes where female characters are shown to be victorious in close-quarters physical combat against male opponents, making it challenging to describe outcomes.

The characters in "Blue Eye Samurai" are original creations for the series, not adaptations of established canonical figures or historical persons. Therefore, there is no prior gender baseline from source material or history for any character to have been swapped from.

As an original animated series, "Blue Eye Samurai" does not adapt characters from prior canon. While Princess Akemi, a Japanese character, is voiced by a Korean-American actress, this is considered an ethnic/national shift within the same broader racial category (Asian), which is explicitly excluded from the definition of a race swap.