Broad City provides a consistently positive and affirming portrayal of LGBTQ+ characters. Ilana's bisexuality is a normalized, integral part of her identity, depicted with humor and dignity. The show seamlessly integrates diverse queer relationships and identities, fostering an inclusive, sex-positive environment that celebrates various forms of love without judgment or harmful stereotypes.

Broad City features Pano, Ilana's trans male cousin, as a recurring character. His trans identity is presented with dignity and is fully accepted by the other characters, without being a source of conflict or mockery. The show's portrayal is respectful and normalizes his identity, contributing to a net positive impact through inclusive and affirming representation.

Broad City portrays Judaism primarily through the cultural and familial experiences of its main characters, Abbi and Ilana. While often used for comedic effect, including self-deprecating humor and observations on stereotypes, the depiction is generally affirming, showcasing Judaism as an integral part of their identity and heritage without portraying it as oppressive or foolish.