The series features a prominent queer storyline centered on Caroline Merteuil, a main character who explores her bisexuality. Her relationships with women are depicted as integral to her complex character arc and journey of self-discovery. The narrative portrays her queer identity with agency and complexity, integrating it naturally within the show's manipulative world without presenting it as inherently problematic or a source of ridicule.

The character Annie, an adaptation of Annette Hargrove from the original "Cruel Intentions" film, is portrayed by a Black actress. Annette Hargrove was previously depicted as White in the 1999 movie. This casting decision represents a race swap for a key character.

The series normalizes sexual freedom and manipulative relationships within a wealthy, blended family, while actively subverting traditional gender roles and undermining parental authority.