Fullmetal Alchemist (2003) does not feature any explicitly identifiable LGBTQ+ characters or themes. The narrative focuses on other aspects, and queer identities are not depicted or explored within the series.

Fullmetal Alchemist (2003) does not feature any identifiable transsexual characters or themes within its narrative. The story primarily focuses on alchemy, war, and the search for the Philosopher's Stone, without engaging with transsexual identities or experiences, thus resulting in no depiction.

The 2003 Fullmetal Alchemist anime adapts the manga without altering the established genders of its core characters. While some Homunculi differ from the manga, characters like Sloth in the 2003 anime are considered original creations for that specific adaptation's divergent storyline, rather than gender-swapped versions of existing manga characters.

The 2003 anime adaptation of Fullmetal Alchemist faithfully portrays its characters' visual appearances, including race, as established in the original manga. There are no instances where a character canonically depicted as one race in the source material is portrayed as a different race in this adaptation.