Hell's Paradise offers a positive portrayal of LGBTQ+ themes primarily through its exploration of gender fluidity and queer-coded relationships. Gender-fluid characters are depicted as divine, challenging binaries, while sapphic-coded bonds are shown with depth and respect. The series avoids stereotypes and sensationalism, promoting a progressive view on identity and acceptance.

The show features Yuzuriha, a skilled kunoichi, who engages in and wins close-quarters physical combat against male opponents. For example, she defeats Senta in a sparring match, demonstrating her superior ninja skills. She also successfully handles various other male opponents through her cunning and combat prowess.

Buddhism is deeply integrated into the series' world-building, iconography, and thematic elements, contributing to a mythic and otherworldly tone. The narrative utilizes Buddhist concepts and imagery to enrich the setting and character identities rather than to critique the religion itself.