Ghost in the Shell does not feature any identifiable LGBTQ+ characters, relationships, or themes. Its narrative centers on existential questions regarding consciousness and the human-machine interface, leading to a net impact of N/A for LGBTQ+ portrayal.

Ghost in the Shell explores themes of identity, consciousness, and the human condition in a future where cybernetic bodies are common. While it delves into the philosophical concept of a 'ghost' within a 'shell,' the film does not feature identifiable transsexual characters or explicitly address themes of gender identity or transition. Its focus is on the nature of humanity and technology, not gender affirmation.

The 1995 film adaptation of "Ghost in the Shell" faithfully retains the established genders of its core characters, including Major Motoko Kusanagi and the members of Section 9, as depicted in the original manga. No character canonically established as one gender in the source material is portrayed as a different gender in this movie.

The 1995 animated film adapts its Japanese manga source material, portraying its characters, such as Major Motoko Kusanagi, consistently with their established Japanese ethnicity and appearance. There are no instances where a character's race was changed from the source.