Kenny vs. Spenny frequently uses homophobic slurs, cross-dressing for comedic humiliation, and jokes based on gay stereotypes. These elements are consistently employed for shock value and mockery, resulting in a problematic portrayal where LGBTQ+ identity is a source of ridicule and degradation.

The show frequently uses Christian symbols, practices, and figures (e.g., Jesus, priests, the Bible) for irreverent, often crude, comedic effect, primarily through Kenny's character. The narrative frames these portrayals as sources of humor, without offering any counterbalancing respect or nuance, thus validating a dismissive and mocking stance.

Kenny's Jewish heritage is occasionally referenced, often in a self-deprecating or stereotypical manner, or by using sacred texts for comedic purposes. The show's humor derives from this irreverence and boundary-pushing, without providing any positive or nuanced counter-narrative, thereby reinforcing a dismissive portrayal.