The series includes very brief, incidental depictions of same-sex encounters for minor characters like Arthur Shelby Jr. and Isaiah Jesus. These moments are not central to their arcs, lack significant exploration of identity or societal impact, and neither affirm nor denigrate LGBTQ+ themes, resulting in a neutral overall portrayal.

The series frequently depicts Christian institutions and figures, such as Father Hughes, as corrupt, hypocritical, or complicit in societal ills. While some characters find personal solace, the overarching narrative critiques the church's moral failings and its use as a facade for power, rather than affirming its virtues.

Judaism is portrayed through characters like Alfie Solomons, whose identity is deeply tied to his Jewish heritage. The narrative explicitly condemns antisemitism and the rise of fascist ideologies, positioning the audience to sympathize with Jewish characters facing prejudice and violence.