Switched at Birth featured multiple LGBTQ+ characters, including lesbian and transgender individuals, whose storylines were handled with sensitivity. The show consistently depicted these characters with dignity, complexity, and agency, affirming their worth and relationships. Obstacles were framed as external, reinforcing a respectful and empathetic stance toward queer identity.

Switched at Birth features Alex, a trans man, whose storyline respectfully explores his transition and experiences. The show portrays him with dignity, addressing challenges as external forces and affirming his identity through his relationships and personal growth, resulting in a net positive impact.

The film portrays Christianity through characters like Kathryn, showing faith as a source of comfort, community, and moral guidance. While individual characters may struggle or be imperfect, the narrative consistently presents Christian values and practices with respect and nuance.

The show portrays Jewish characters and their traditions with respect, highlighting the warmth of family and community, and presenting their faith as a meaningful part of their identity without negative critique.