The Chi features multiple LGBTQ+ characters across different generations, exploring themes of self-discovery, love, and acceptance within the Black community. While initial struggles with prejudice are depicted, the narrative consistently affirms queer identities and relationships with dignity, complexity, and empathy, leading to a net positive portrayal.

The Chi features Bakari, a trans man, as a central character and love interest. His portrayal is affirming, depicting him with dignity, agency, and a supportive relationship. The show respectfully explores his identity and challenges, framing obstacles as external and promoting understanding and acceptance within the narrative.

The series consistently portrays Christianity, its churches, and its adherents as a foundational pillar of the community, offering solace, moral guidance, and a strong sense of belonging amidst adversity. While individual characters or institutions may exhibit flaws or hypocrisy, the narrative generally affirms the positive role of faith in providing hope and resilience, rather than critiquing the religion itself.