The series includes Timo Proud, an openly gay recurring character. His sexuality is presented as a matter-of-fact aspect of his identity, neither central to the plot nor a source of conflict or affirmation. He is depicted as a helpful and respected individual, leading to a neutral overall portrayal of LGBTQ+ themes.

The Finder features a transgender character, Dr. Aris Thorne, portrayed as a respected professional. The narrative also respectfully explores a deceased character's transition, framing her secrecy as a response to external societal pressures. The episode ultimately affirms the dignity and worth of transsexual lives and relationships, leading to a net positive portrayal.

Leo Knox, a character described as white in Richard Greener's 'The Locator' book series, which serves as the source material, is portrayed by Michael Clarke Duncan, a Black actor, in the show.

The show consistently portrays Christian characters, such as nuns and priests, as sympathetic, virtuous, and helpful individuals who contribute positively to their communities. Christian institutions are often depicted as places of refuge and support, aligning the narrative with the dignity and positive aspects of the faith.