The film "Big Trouble" does not feature any identifiable LGBTQ+ characters or themes within its narrative. The plot focuses on a chaotic series of events involving a nuclear device, a hitman, and various eccentric individuals, without incorporating queer identities or storylines.

The film "Big Trouble" does not feature any identifiable transsexual characters or themes. Although its source novel included a transsexual character, this aspect was not carried over or explicitly depicted in the movie adaptation, resulting in no portrayal.

The film features several female characters who are involved in the chaotic plot, but none are depicted engaging in or winning close-quarters physical combat against male opponents. Their roles are primarily comedic or as targets of the various factions.

The film "Big Trouble" (2002) is an adaptation of Dave Barry's novel. A review of the main and significant characters in both the book and the movie reveals no instances where a character's established gender from the source material was changed for the film.