Ghost Killer does not portray or focus on the LGBTQ community within its narrative. The film centers on a supernatural action story exploring female empowerment and abusive relationships, with no identifiable LGBTQ+ characters or themes present in the plot or character arcs.

The film *Ghost Killer* (2025) does not feature any transsexual characters or themes related to gender or sexual transformation. The narrative focuses on a supernatural revenge plot involving a possessed college student and a ghost, with no elements that depict or address transsexual identities or experiences.

The film features a male ghost possessing a female body, but this is explicitly stated as a narrative device and not a change to the established genders of the characters. No characters are portrayed on-screen with a gender different from their canonical or established gender within the story.

The film's major characters, Fumika, Hideo Kudo, and Toshihisa Kagehara, are all described as Japanese and are portrayed by Japanese actors. The casting maintains ethnic authenticity, aligning with the characters' backgrounds and the film's Japanese setting, with no indication of a race swap.