Kiss of the Spider Woman (2025) offers a complex, empathetic, and nuanced portrayal of LGBTQ+ themes through Luis Molina, a closeted gay man with gender nonconforming identity. The film explores queer love, identity, and resilience under political oppression, using art and fantasy to affirm dignity and humanity. It critiques societal homophobia while delivering a bittersweet yet ultimately positive message.

Kiss of the Spider Woman (2025) features Luis Molina, a transsexual or gender non-conforming character, whose identity is central to the narrative. The film offers a respectful, nuanced, and empathetic portrayal, exploring the complexities of his identity and his evolving relationship with Valentín. This depiction emphasizes dignity and emotional depth, contributing to themes of acceptance and human connection, aligning with a positive overall impact.

The character Luis Molina, originally a cisgender gay man in the source material, is portrayed in the 2025 film as gender non-conforming or possibly genderqueer/trans-leaning. This shift in on-screen gender presentation from his canonical cisgender male identity constitutes a gender swap.