Based on available information, 'The Substance' does not feature explicit LGBTQ+ characters or themes. The film's narrative centers on critiques of societal beauty standards, ageism, and misogyny, focusing on female identity and body politics without notable LGBTQ+ representation.

The movie does not contain any action or adventure elements.

The film centers on a female protagonist who creates a younger female version of herself. Both the original and created characters are explicitly female, and the narrative explores themes of female identity and aging, not gender transformation or swapping from a pre-established gender.

The Substance is an original film with no prior source material or historical figures. Therefore, no characters were previously established as a different race, and no race swap occurred.