Mickey 17 does not explicitly portray transsexual characters or themes. While it explores broader concepts of identity and humanity through cloning, these are not specifically focused on transsexual experiences. Any interpretation of transsexual representation would be metaphorical rather than direct.

Based on available pre-release information, trailers, and reviews for 'Mickey 17', there are no detailed descriptions or explicit mentions of female characters engaging in and winning direct physical combat against male opponents. Combat scenes referenced primarily focus on the male protagonist.

The film's characters, including the protagonist Mickey Barnes, maintain consistent gender identities with their established roles in the source novel *Mickey7*. There is no indication of any character's gender being altered for the film adaptation.

The film adapts a science fiction novel where character ethnicities are largely unspecified, except for the protagonist whose casting aligns with the source material. The diverse cast reflects a futuristic, multinational setting rather than altering established racial identities from prior canon.