Final Space includes Ash Graven, a non-binary character whose identity is depicted with dignity and complexity. The narrative integrates this identity without making it a source of ridicule or a defining negative trait, contributing to an overall affirming portrayal.

The series features Quinn Ergon, a skilled soldier, who repeatedly engages in and wins close-quarters physical fights against multiple male opponents, including Infinity Guard soldiers.

The series primarily depicts a chosen family formed by a diverse crew, normalizing alternative family structures. While a strong biological father-son bond is present, the narrative emphasizes non-traditional familial relationships and fluid roles.