Lyla in the Loop centers on a diverse, multicultural community and themes of creativity and STEM learning for young children. The show's narrative and character representations do not explicitly include or focus on LGBTQ+ identities or themes, concentrating instead on racial and cultural diversity and family structures.

Lyla in the Loop does not feature transsexual characters or themes. The series centers on a young Black girl, her family, and friends, exploring problem-solving and community life without addressing transsexual identities or issues.

The movie does not contain any action or adventure elements.

Lyla in the Loop is an original animated series featuring characters created specifically for the show. As there are no pre-existing characters from source material or historical records, no instances of gender swapping are present.

The show features original characters whose established African-American and Jamaican heritage is authentically matched by the voice actors. There is no prior canon or historical record indicating a change in race for any character.