The series "Ninja Turtles: The Next Mutation" does not feature any identifiable LGBTQ+ characters or themes. The narrative focuses on the adventures of the Teenage Mutant Ninja Turtles and their new member, Venus de Milo, battling various villains, without exploring queer identities or relationships.

The series "Ninja Turtles: The Next Mutation" does not feature any identifiable transsexual characters or themes. The narrative focuses on the Teenage Mutant Ninja Turtles and their adventures, with no elements related to transgender identity or experiences.

The series introduces Venus De Milo, a new female ninja turtle. However, she is an original character created for this installment, not a gender-swapped version of an existing male character from prior canon. The original four turtles retain their established genders.

The core characters (Turtles, Splinter) are non-human, making the concept of a 'race swap' inapplicable to them. Human characters like April O'Neil are portrayed consistently with their established race from previous iterations. No established character's race was changed.