Based on available information for 'Red Dead Redemption: The Complete Series, 2010', there are no identifiable LGBTQ+ characters or themes present within the narrative. The film, a fan-made adaptation of the video game, does not feature any explicit LGBTQ+ representation.

Based on the provided details for "Red Dead Redemption: The Complete Series, 2010," there is no information indicating the presence of transsexual characters or themes. Therefore, an assessment of their portrayal cannot be made, as there is no depiction to evaluate.

The film, a compilation of cutscenes from the video game, features female characters such as Bonnie MacFarlane. While these characters are strong and participate in action sequences, their combat involvement is primarily through the use of firearms. There are no scenes depicting a female character defeating one or more male opponents in close-quarters physical combat using hand-to-hand or melee weapons.

This 'series' is a compilation or machinima of the Red Dead Redemption video game, utilizing the original game's characters and voice actors. All major characters, such as John Marston and Abigail Marston, retain their established genders from the source material.

The series adapts the video game 'Red Dead Redemption.' Key characters like John, Jack, and Abigail Marston are canonically white in the source material. The listed actors, who are the original voice actors for these characters, are also white, indicating no race swap.