The show features Patricia (Shaina), a powerful Silver Saint, who engages in and wins multiple close-quarters physical fights against male opponents, including Seiya and armed soldiers, using martial arts and her cosmic abilities.

The adaptation features significant gender swaps for established characters. Andromeda Shun, canonically male in the source material, is portrayed as female. Similarly, Milo, the Scorpio Gold Saint, is also depicted as female, diverging from the original male portrayal.

The character of Milo, the Scorpio Gold Saint, who was originally depicted as a male of ambiguous European descent in the source material, is portrayed as a Black female in the 2019 adaptation. This constitutes a race swap.