The Daily Show consistently offers a positive portrayal of LGBTQ+ characters and themes. Through satirical commentary and news segments, it critiques prejudice and discrimination, advocates for LGBTQ+ rights, and presents queer individuals with dignity and respect, affirming the worth of LGBTQ+ lives.

The Daily Show, over its extensive run, has largely presented a positive net impact regarding transsexual characters and themes. While early satirical content might have varied, the show has increasingly used its platform to critique anti-trans prejudice, advocate for trans rights, and feature trans voices with dignity, affirming the worth of trans lives.

The show frequently satirizes Christian fundamentalism, political figures misusing faith, and institutional hypocrisy, highlighting problematic aspects and their societal impact.

The show consistently critiques Islamophobia and bigotry against Muslims, often distinguishing between extremist groups and the broader faith, positioning the audience to sympathize with victimized adherents.

The show generally treats Judaism with respect, often defending Jewish people from antisemitism and focusing critiques on political actions rather than the faith itself.