Web Therapy offers a net positive portrayal of LGBTQ+ characters. Fiona's husband, Kip, has a central arc of coming out and finding happiness in his gay identity. Other queer characters are depicted with complexity, and the show's comedic elements satirize societal reactions and individual quirks rather than denigrating LGBTQ+ lives or relationships.

The show features a recurring client who reveals they are transitioning. This plot point is used for comedic effect, primarily through the protagonist's self-absorbed and unprofessional reactions. The portrayal avoids strong positive or negative messaging, focusing instead on character-driven humor.

The show portrays Christian characters with their individual flaws and quirks, often satirizing human hypocrisy or naivete rather than the faith itself. When characters like Fiona Wallice express cynicism towards religious beliefs, the narrative often highlights Fiona's own self-centeredness and lack of empathy, positioning her as the comedic target rather than endorsing her critique of Christianity.