Who Is America? incorporates LGBTQ+ themes within its satirical framework, primarily through characters who express prejudiced views to expose the biases of interviewees. The portrayal is neither overtly affirming nor directly denigrating, as problematic elements serve a broader critical purpose rather than endorsing ridicule.

The series incorporates discussions of gender identity and fluidity through satirical characters. These segments present the topic in an exaggerated or absurd manner to provoke reactions from interviewees, primarily for comedic effect. The portrayal does not feature transsexual characters with dignity or complexity, instead using the concept as a source of mockery or confusion within its satirical framework.

Who Is America? is a satirical political comedy series that does not feature significant narrative content or themes related to family structures, roles, or values. The series therefore offers no discernible portrayal of family life norms.

The series frequently portrays conservative Christian figures and their political allies as hypocritical, bigoted, or easily swayed by extreme ideologies. The satire targets the misuse of Christian values to justify prejudice and political agendas, presenting these specific adherents and their institutions in a fundamentally problematic light without significant counterbalancing nuance.

The series often exposes Islamophobia and the irrational fears surrounding Muslim communities through its satirical encounters. The narrative consistently frames the prejudice against Islam as wrong, positioning the audience to sympathize with the religion and its adherents when they are targeted by bigotry.

The series utilizes characters, such as Erran Morad, to expose antisemitism and highlight the absurdity of prejudiced views against Jewish people. The narrative framing consistently positions the audience to condemn bigotry and sympathize with the target of such prejudice, aligning with the dignity of the faith by attacking its detractors.