Enola Holmes (2020) focuses on its protagonist's adventures and themes of independence and societal expectations in Victorian England. The film does not feature any identifiable LGBTQ+ characters or explore related themes, resulting in no specific portrayal of the LGBTQ+ community within its storyline.

The film "Enola Holmes" does not feature any identifiable transsexual characters or themes. The narrative primarily focuses on Enola's journey to find her mother and her involvement in a mystery related to women's suffrage and societal change in Victorian England, without touching upon transgender identity.

The film features characters like Sherlock and Mycroft Holmes, who maintain their established male gender from the original canon. New characters, such as Enola Holmes, are portrayed with the gender they were created with in the source novels. No significant character's gender was altered from their canonical or historical representation.

The film's main characters, including Enola, Sherlock, and Mycroft Holmes, are portrayed by actors whose race aligns with their established canonical depictions. New characters introduced in the film do not qualify as race swaps.