Clash of the Titans (2010) does not include any discernible LGBTQ+ characters or themes. The narrative centers on traditional mythological figures and their heterosexual relationships, resulting in no portrayal of queer identity within the film's scope.

Clash of the Titans (2010) does not feature any identifiable transsexual characters or themes. The narrative is centered on mythological quests and battles, with no elements related to gender identity or transition present in the story.

The film features several female characters, including Io, Andromeda, and Medusa. Io and Andromeda do not engage in physical combat. Medusa defeats male opponents, but her victories are achieved solely through her supernatural gaze, which turns victims to stone, rather than through physical combat skills or strength.

The 2010 film is an adaptation of Greek mythology and a remake of the 1981 movie. All major and minor characters derived from the source material or previous installment retain their established gender in the 2010 version.

The film adapts Greek mythology and remakes a 1981 movie. Key characters like Perseus, Andromeda, and the Olympian gods, traditionally depicted as white in source material and prior adaptations, are portrayed by white actors in the 2010 film. No instances of a race swap were identified.