Devilman Crybaby features a diverse cast with various sexual orientations and gender expressions, including gender non-conforming characters. However, the narrative does not explicitly present or explore characters who identify as transsexual, nor does it delve into themes specific to transsexual identity. Therefore, a direct evaluation of its portrayal of transsexual characters and themes is not applicable.

The show features powerful female demons and Devilmen, such as Silene and Miko Kuroda. While they engage in intense combat, their victories are primarily achieved through overwhelming demonic powers rather than skill-based physical combat or martial arts against multiple male opponents. No scenes depict a female character defeating multiple male opponents through skill or strength in close-quarters combat.

All major characters in "Devilman Crybaby" maintain the same gender as established in the original "Devilman" manga series. No characters canonically established as one gender were portrayed as a different gender.

Devilman Crybaby is an adaptation of the Devilman manga. The series maintains the racial depictions of its primary characters, who are consistently portrayed as Japanese, aligning with their original source material. No characters established as one race in the manga are depicted as a different race in this adaptation.