The Haunting of Hill House does not feature any identifiable transsexual characters or themes. The narrative focuses on the Crain family's experiences with trauma, grief, and a haunted house, without incorporating transgender identities or related storylines.

The movie does not contain any action or adventure elements.

The 2018 series adapts the novel by Shirley Jackson, reimagining the core characters as a family. While the narrative and relationships are significantly altered, characters retaining names from the source material (Eleanor, Theodora, Luke) maintain their original genders. No established character from the novel is portrayed as a different gender.

The show is an adaptation of Shirley Jackson's novel, but the main characters are largely original creations or significantly re-imagined. The race of the few characters sharing names with the novel was not explicitly defined in the source material as being different from their on-screen portrayal.